COMPLEOCiD-EO: Synergistic functionality for best performance in aquaculture.

What is COMPLEOCiD-E05?

COMPLEOGD-Ee is a unique combination of organic acids and their salts, phosphoric acid, and protected organic acids and essential oils.

How does COMPELEOCID-EO work?

• COMPLEOCID-Eeconsists of 3 active ingredient groups and is multifunctional:
  . Free organic acids and their salts
  . Free inorganic acid
  . Microencapsulated acid and essential oils
• COMPLEOCM-EIPactive ingredients are selected to act in the mouth, stomach as well as in the small and large intestine.
• COMPLEOCiD-E0 ® is one hundred percent active for the animals and supplies highly available calcium and phosphorus for a successful diet formulation.
• COMPLEOCiD-E0 ® is an easy to handle, non-corrosive feed additive which is developed for safe handling.
• COMPLEOCiD-E0 ® helps to reduce buffering capacity in the feed.

COMPLEOCiD-E0°— Benefits of micro-encapsulated organic acids:

• Antimicrobial effects due to strong organic acids form barrier against ascending infections from hindgut to foregut.
• Effective throughout the GIT.
• Nutritive value of organic acids as fast energy source.
• Continuous release of active ingredients throughout the GIT.

Efficacy of COMPELEOCID-EO Complex Compared to single acids and their salts:

COMPLEOCiD-EO in aquaculture:

Schrimp trial, Univ. Kasetart, Thailand, 2012

*lowest dosage with statistically significant difference from control group.

Where is COMPLEOCO-E0° working?

Feed:

• Antimicrobial effect.
• Nutritional effects (Ca & P minerals/energy)
• Reduction of buffering capacity

Stomach:

• Reduction of the pH (formic, lactic, phosphoric acid).
• Activation of proteolytic enzymes (better protein digestion).

Small Intestine:

• Antimicrobial effect (e.g. gram negative bacteria with lactic acid, and local pH reduction).
• Stimulation of pancreas secretion (pH effect 9 feedback from the stomach); better Ca and P digestion.

Large Intestine:

• Antimicrobial effects due to microencapsulated essential oils and strong organic acids.
• Stimulation of non specific immunity (lactic acid).

COMPLEOCID-EC – Antimicrobial effects of essential oils and organic acids:

• Essential oils increase permeability of the cell wall of pathogenic bacteria.
  – essential oils have the ability to change the outer membrane of gram-negative bacteria.
  – resulting in the inactivation of the cell protein.
• Organic acids, now also in dissociated form (anion- and cation+), can pass
  through the cell wall.
  – therefore also more efficiency at higher pH levels for instance in the intestine.

COMPLEOCiD-EO Unique Selling Propositions (USP’s):

1. Better palatability and higher feed intake.
2. pH-lowering effect in the stomach reaching pH 3 – 4 locally.
3. Preventive and active antimicrobial effects.
4. Protection throughout the GIT.
5. High bioavailable Ca- and P-content.
6. Reduce Buffering Capacity in feed formulation.
7. Better performance (DWG, FCR, health, ROI).
8. 100% active.
9. Safe and easy handling.

Dosage Advice:

Shrimp & Fish Dosage (kg/mt)
All stages 3.0
in EMS cases 6.0